Relations between Exposure to o ‐Dichlorobenzene and Concentrations of Urinary Metabolites
نویسندگان
چکیده
منابع مشابه
Quantitative Determination of Urinary Metabolites o-Dichlorobenzene Using a Gas Chromatograph of
o-Dichlorobenzene (o-DCB) is used as an organic solvent, as a chemical intermediate, and as a heat transfer medium. In humans, o-DCB is metabolized to 2,3and 3,4-dichlorophenols, and 3,4and 4,5-dichlorocatechols, and these metabolites are eliminated via the kidneys. In this study, we tried to determine the concentrations of urinary 2,3and 3,4-dichlorophenols using a gas chromatograph (GC). When...
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Toluene is known to be the most popular solvent for industrial use,1,2) and attention has been paid on the possibility of biological monitoring of toluene exposure by urinalysis for metabolites such as hippuric acid and o-creso1.3-5) In a previous study6) on possible ethnic difference in toluene metabolism, it was disclosed that Chinese toluene workers excrete less hippuric acid in urine than t...
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BACKGROUND Marijuana is seeing increased therapeutic use, and is the world's third most-popular recreational drug following alcohol and tobacco. This widening use poses increased exposure to potentially toxic combustion by-products from marijuana smoke and the potential for public health concerns. OBJECTIVES To compare urinary metabolites of polycyclic aromatic hydrocarbons (PAHs) and volatil...
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OBJECTIVES This study aimed to develop a physiologically based pharmacokinetic model for chlorobenzene and to investigate the effect of variation in exposure to chlorobenzene on the chlorobenzene concentration in blood and the urinary concentration of 4-chlorocatechol. METHODS A physiologically based pharmacokinetic model was developed and the simulated results of urinary 4-chlorocatechol con...
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ژورنال
عنوان ژورنال: Journal of Occupational Health
سال: 1997
ISSN: 1341-9145,1348-9585
DOI: 10.1539/joh.39.124